Clemson small road favorites over South Carolina College Football Picks & College Football Odds - I think Clemson will run the football like they have the last 5 games. The difference between Parker and Garcia will be the play action pass. SC defensive backs will be looking for the run which will open up the passing game. Parker steps up in the pocket a little better than Garcia. If SC can run the football that will give Garcia a better chance. If SC cannot run the football then Garcia throws a ton of interceptions. Bodog.com list College Football Odds South Carolina +3.5 home underdogs to Clemson. 

The Gamecocks pride themselves on defense, but have lost three straight in the tough SEC - at Tennessee, at Arkansas and home against Florida. Clemson enters the game as one of the more dangerous teams in the country, highlighted by the brilliance of C.J. Spiller, who has accounted for more than 1300 all-purpose yards this season. College Football Sports Betting Odds list the total for this Clemson vs. South Carolina game is set at 45 points. 

College Football Predictions I like Clemson big in this spot. Any team that can hang with TCU and beat the U in there own stadium got my vote of confidence in a game. USC will be in a serious dog fight with Clemson. At home the Gamecocks are averaging 24.7 scoring, and holding teams to 16.7 points scored on defense. The Clemson Tigers are 2-2 while on the road this season, 6-2 against conference opponents and 2-1 against non-conference opponents. College Football Picks Bet on Clemson against the College Football Betting Line spread at Bodog.com.

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